Article
Association of matrix metalloproteinase-2 gene variants with diabetic nephropathy risk.
The journal of gene medicine - 1 Nov 2023
Sarray Sameh, Lamine Laila Ben, Dallel Meriem, Ezzidi Intissar, Sellami Nejla, Turki Amira, Moustafa Amgad Elbaz El-Agroudy, Mtiraoui Nabil
Abstract excerpt
BACKGROUND: Diabetic nephropathy is a highly destructive microvascular complication of diabetes. Genetic predisposition is involved in the pathogenesis of diabetic nephropathy, with multiple allelic polymorphisms associated with the development and progression of the disease, thereby increasing the overall risk. To date, no study is available that shows the association of matrix metalloproteinase-2 (MMP-2) gene...
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