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Article

The utility of the Ion Torrent PGM next generation sequencing for analysis of the most commonly mutated genes among patients with colorectal cancer in India.

Indian journal of cancer - 1 Jan 2000

Mehra Simmi, Tiwari Aseem Kumar, Mehta Swati Pabbi, Sachdev Ritesh, Rajvanshi Chhavi, Chauhan Rajni, Saini Abhishek, Vaid Ashok

Abstract excerpt

Background: The requirement for the mutation analysis for Kirsten rat sarcoma viral oncogene (KRAS) in colorectal cancer (CRC) is rapidly increasing as it is a predictive biomarker and also, its absence signifies response to anti-epidermal growth factor receptor (anti-EGFR) antibody treatment. The aim of our study was to investigate the pathological diagnosis and distribution of KRAS mutations in colorectal...

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PMID: 33753628
DOI: 10.4103/ijc.IJC_723_19

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