Article
Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort).
Journal of the American College of Cardiology - 27 Aug 2013
Ferguson Jane F, Matthews Gregory J, Townsend Raymond R, Raj Dominic S, Kanetsky Peter A, Budoff Matthew, Fischer Michael J, Rosas Sylvia E, Kanthety Radhika, Rahman Mahboob, Master Stephen R, Qasim Atif, Li Mingyao, Mehta Nehal N, Shen Haiqing, Mitchell Braxton D, O'Connell Jeffrey R, Shuldiner Alan R, Ho Weang Kee, Young Robin, Rasheed Asif, Danesh John, He Jiang, Kusek John W, Ojo Akinlolu O, Flack John, Go Alan S, Gadegbeku Crystal A, Wright Jackson T, Saleheen Danish, Feldman Harold I, Rader Daniel J, Foulkes Andrea S, Reilly Muredach P
Abstract excerpt
OBJECTIVES: This study sought to identify loci for coronary artery calcification (CAC) in patients with chronic kidney disease (CKD). BACKGROUND: CKD is associated with increased CAC and subsequent coronary heart disease (CHD), but the mechanisms remain poorly defined. Genetic studies of CAC in CKD may provide a useful strategy for identifying novel pathways in CHD. METHODS: We performed a candidate gene study...
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