Article
Vascular calcification in chronic kidney disease associated with pathogenic variants in ABCC6.
Gene - 15 Nov 2024
Schott Clara, Dilliott Allison A, Wang Jian, McIntyre Adam D, Son Surim, Colaiacovo Samantha, Baker Cadence, Gunaratnam Lakshman, House Andrew A, Susan Huang Shih-Han, Iyer Hariharan, Johnson John, Lotfy Khaled, Masellis Mario, Munoz Douglas P, Rehman Faisal, Roshanov Pavel S, Swartz Richard H, Weir Matthew A, Hegele Robert A, Connaughton Dervla M
Abstract excerpt
Vascular calcification is prevalent in chronic kidney disease (CKD). Genetic causes of CKD account for 10-20% of adult-onset disease. Vascular calcification is thought to be one of the most important risk factors for increased cardiovascular morbidity and mortality in CKD patients and is detectable in 80% of patients with end stage kidney disease (ESKD). Despite the high prevalence of vascular calcification in...
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