Polymorphism in the HMOX1 gene is associated with high levels of fetal hemoglobin in Brazilian patients with sickle cell anemia.

doi:10.3109/03630269.2013.789438

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Article

Polymorphism in the HMOX1 gene is associated with high levels of fetal hemoglobin in Brazilian patients with sickle cell anemia.

Hemoglobin - 1 Jan 2013

Gil Gislene P, Ananina Galina, Oliveira Mariana B, Costa Fernando F, Silva Márcio J, Santos Magnun N N, Bezerra Marcos A C, Hatzlhofer Betânia L D, Araujo Aderson S, Melo Mônica B

Abstract excerpt

The aim of this study was to investigate the association between three polymorphisms involved in the oxidative stress pathway and fetal hemoglobin (Hb F) levels in patients with sickle cell anemia in a Brazilian population. One hundred and seven patients with sickle cell anemia were recruited for genomic DNA extraction. The levels of Hb F, sex and age were evaluated. Three polymorphisms, rs4673:T>C and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23725037
DOI: 10.3109/03630269.2013.789438

Genes

HMOX1
CYBA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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