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Article

Significance of heme oxygenase-1(HMOX1) gene on fetal hemoglobin induction in sickle cell anemia patients.

Scientific reports - 28 Oct 2020

Hariharan Priya, Chavan Vrushali, Nadkarni Anita

Abstract excerpt

Though the patients with sickle cell anemia (SCA) inherit same genetic mutation, they show considerable phenotypic heterogeneity. It has been observed that patients with elevated fetal hemoglobin (HbF) levels have a relatively mild clinical course. There is sparse literature on the association of higher HbF levels leading to reduction in the oxidative stress in SCA patients. Hence in this study, the significance...

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Share to Anemia, Sickle Cell
Share to Child, Preschool
Share to Fetal Hemoglobin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Heme Oxygenase-1

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Share to Polymorphism, Restriction Fragment Length

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Source

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Identifiers

PMID: 33116199
DOI: 10.1038/s41598-020-75555-y
PMCID: PMC7595119

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