Article
Maintenance of melanophore morphology and survival is cathepsin and vps11 dependent in zebrafish.
PloS one - 1 Jan 2013
Clancey Lauren F, Beirl Alisha J, Linbo Tor H, Cooper Cynthia D
Abstract excerpt
Here, we characterize a Danio rerio zebrafish pigment cell mutant (melanophore integrity mutant), which displays a defect in maintenance of melanophore and iridophore number. Mapping and candidate gene analysis links the melanophore integrity mutant mutation to the vacuolar protein sorting 11 (vps11(w66)) gene. Quantification of vps11(w66) chromatophores during larval stages suggests a decrease in number as...
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