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Article

oca2 Regulation of chromatophore differentiation and number is cell type specific in zebrafish.

Pigment cell & melanoma research - 1 Mar 2014

Beirl Alisha J, Linbo Tor H, Cobb Marea J, Cooper Cynthia D

Abstract excerpt

We characterized a zebrafish mutant that displays defects in melanin synthesis and in the differentiation of melanophores and iridophores of the skin and retinal pigment epithelium. Positional cloning and candidate gene sequencing link this mutation to a 410-kb region on chromosome 6, containing the oculocutaneous albinism 2 (oca2) gene. Quantification of oca2 mutant melanophores shows a reduction in the number...

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PMID: 24330346
DOI: 10.1111/pcmr.12205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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