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Article

Detection of genetic variations in coagulopathy-related genes using ramified rolling circle amplification.

BioMed research international - 1 Jan 2014

Smith James H, Cui Miao, Zhang David Y, Beals Thomas P, Ye Fei

Abstract excerpt

We evaluated single nucleotide polymorphism (SNP) detection via a target-capture, C-probe ligation, and RAM assay in a single-blind comparison to clinical samples that had been tested with FDA-cleared tests for up to 4 different vascular disease-related SNPs. In the RAM assay circulizable linear probes (C- or padlock probes) were annealed directly to genomic DNA, processed on a largely automated platform, and...

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Identifiers

PMID: 24719880
DOI: 10.1155/2014/641090
PMCID: PMC3955693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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