Article
Advanced type 1 diabetes is associated with ASIC alterations in mouse lower thoracic dorsal root ganglia neurons.
Cell biochemistry and biophysics - 1 Jan 2014
Radu Beatrice Mihaela, Dumitrescu Diana Ionela, Marin Adela, Banciu Daniel Dumitru, Iancu Adina Daniela, Selescu Tudor, Radu Mihai
Abstract excerpt
Acid-sensing ion channels (ASICs) from dorsal root ganglia (DRG) neurons are proton sensors during ischemia and inflammation. Little is known about their role in type 1 diabetes (T1D). Our study was focused on ASICs alterations determined by advanced T1D status. Primary neuronal cultures were obt...
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