Interaction between calcineurin inhibitors and IL-28B rs12979860 C>T polymorphism and response to treatment for post-transplant recurrent hepatitis C.

doi:10.1016/j.dld.2013.04.006

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Article

Interaction between calcineurin inhibitors and IL-28B rs12979860 C>T polymorphism and response to treatment for post-transplant recurrent hepatitis C.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Nov 2013

Bitetto Davide, De Feo Tullia, Mantovani Martina, Falleti Edmondo, Fabris Carlo, Belli Luca Saverio, Fagiuoli Stefano, Burra Patrizia, Piccolo Giuseppe, Donato Maria Francesca, Toniutto Pierluigi, Cmet Sara, Cussigh Annarosa, Viganò Raffaella, Airoldi Aldo, Pasulo Luisa, Colpanij Maria, De Martin Eleonora, Gambato Martina, Rigamonti Cristina

Abstract excerpt

BACKGROUND: The impact of calcineurin inhibitors on achievement of sustained virological response to antiviral therapy for post-transplant recurrent hepatitis C is controversial. This study aimed at investigating the interactions between calcineurin inhibitors and interleukin-28B (IL-28B) gene polymorphisms and sustained virological response. METHODS: Retrospective study of 147 liver transplant recipients with...

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PMID: 23722013
DOI: 10.1016/j.dld.2013.04.006

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