Article
Impact of donor and recipient IL28B rs12979860 genotypes on hepatitis C virus liver graft reinfection.
Journal of hepatology - 1 Aug 2011
Lange Christian M, Moradpour Darius, Doehring Alexandra, Lehr Hans-Anton, Müllhaupt Beat, Bibert Stephanie, Bochud Pierre-Yves, Antonino Anca T, Pascual Manuel, Farnik Harald, Shi Ying, Bechstein Wolf Otto, Moench Christian, Hansmann Martin-Leo, Sarrazin Christoph, Lötsch Jörn, Zeuzem Stefan, Hofmann Wolf-Peter
Abstract excerpt
BACKGROUND & AIMS: Recent studies have described a major impact of genetic variations near the IL28B gene on the natural course and outcome of antiviral therapy in chronic hepatitis C. We therefore, aimed to explore the impact of donor and recipient genotypes of these polymorphisms on hepatitis C virus (HCV) liver graft reinfection. METHODS: Donor and recipient genotypes of IL28B rs12979860C>T single nucleotide...
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