Interleukin-28B single nucleotide polymorphism of donors and recipients can predict viral response to pegylated interferon/ribavirin therapy in patients with recurrent hepatitis C after living donor liver transplantation.

doi:10.1111/j.1440-1746.2012.07129.x

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Article

Interleukin-28B single nucleotide polymorphism of donors and recipients can predict viral response to pegylated interferon/ribavirin therapy in patients with recurrent hepatitis C after living donor liver transplantation.

Journal of gastroenterology and hepatology - 1 Sept 2012

Kawaoka Tomokazu, Takahashi Shoichi, Takaki Shintaro, Hiramatsu Akira, Waki Koji, Hiraga Nobuhiko, Miki Daiki, Tsuge Masataka, Imamura Michio, Kawakami Yoshiiku, Aikata Hiroshi, Ochi Hidenori, Onoe Takashi, Tashiro Hirotaka, Ohdan Hideki, Chayama Kazuaki

Abstract excerpt

BACKGROUND AND AIM: Interleukin-28B (IL28B) single nucleotide polymorphism (SNP) influences viral response (VR) to interferon (IFN) therapy in patients with hepatitis C. We studied the relationship between VR and the IL28B polymorphism (rs8099917) in patients on long-term pegylated IFN plus ribavirin (PEGIFN/RBV) therapy for recurrent hepatitis C after living-donor liver transplantation (LDLT). METHODS:...

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PMID: 22432893
DOI: 10.1111/j.1440-1746.2012.07129.x

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Interleukin-28B single nucleotide polymorphism of donors and recipients can predict viral response to pegylated interferon/ribavirin therapy in patients with recurrent hepatitis C after living donor liver transplantation.PMID 22432893Read ↗

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