Article
CC genotype donors for the interleukin-28B single nucleotide polymorphism are associated with better outcomes in hepatitis C after liver transplant.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jan 2013
Firpi Roberto J, Dong Huijia, Clark Virginia C, Soldevila-Pico Consuelo, Morelli Giuseppe, Cabrera Roniel, Norkina Oxana, Shuster Jonathan J, Nelson David R, Liu Chen
Abstract excerpt
BACKGROUND/AIMS: Interleukin-28B (IL-28B) polymorphism is the strongest pretreatment predictor of viral clearance in the hepatitis C (HCV) population. Donor and recipient IL-28B genomic background may play an important role in post-transplant HCV recurrence. We sought to examine the role of IL-28B polymorphisms of donor and recipients in liver transplant patients with recurrent HCV and its impact on the response...
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