Article
Recipient interleukin-28B Rs12979860 C/T polymorphism and acute cellular rejection after liver transplantation: role of the calcineurin inhibitor used.
Transplantation - 27 May 2012
Bitetto Davide, Fabris Carlo, Falleti Edmondo, Fornasiere Ezio, Avellini Claudio, Cmet Sara, Cussigh Annarosa, Fontanini Elisabetta, Pirisi Mario, Corradini Stefano Ginanni, Merli Manuela, Molinaro Antonio, Toniutto Pierluigi
Abstract excerpt
BACKGROUND: Interleukin-28 (IL-28B) rs12979860 C/T polymorphism is known to predict the outcome of antiviral therapy in hepatitis C. In addition to its interferon-like and antiviral functions, IL-28B possesses the ability to modulate CD8 T cells function. This study aimed to investigate whether recipient IL-28B polymorphism may have a role in predicting the occurrence of acute cellular rejection (ACR) after liver...
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