Article
The association of IL28B polymorphism and graft survival in patients with hepatitis C undergoing liver transplantation.
PloS one - 1 Jan 2013
Allam Sridhar R, Krüger Bernd, Mehrotra Anita, Schiano Thomas, Schröppel Bernd, Murphy Barbara
Abstract excerpt
Hepatitis C virus (HCV) infection is the leading cause of liver transplantation (LT) in Western countries. Polymorphism in the IL28B gene region has a major impact on the natural history and response to antiviral treatment in HCV. We investigated whether IL28B polymorphism was associated with graft survival in patients with or without HCV undergoing LT. 1,060 adult patients (age >18 years) underwent LT between...
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