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Article

The cellular isopeptidase T deubiquitinating enzyme regulates Kaposi's sarcoma-associated herpesvirus K7 degradation.

Pharmaceutical research - 1 Mar 2015

Xiao Jun, Wu Hui, Peng Lingzhi, Chi Mengdie, Feng Hao

Abstract excerpt

PURPOSE: To understand the regulated degradation of KSHV K7. METHODS: Proteomic screen and immunofluoresence microscopy identified that K7 recruits polyubiquitin chains to membrane fractions; IP and GST pulldown verified the interaction between K7 and Iso T1; Protein stability assay and RQ-PCR de...

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Identifiers

PMID: 23720098
DOI: 10.1007/s11095-013-1064-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23720098-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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