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Article

Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7.

The Journal of biological chemistry - 8 Aug 2003

Holowaty Melissa N, Zeghouf Mahel, Wu Hong, Tellam Judy, Athanasopoulos Vicki, Greenblatt Jack, Frappier Lori

Abstract excerpt

The Epstein-Barr nuclear antigen-1 (EBNA1) protein of Epstein-Barr virus is important for the replication, segregation, and transcriptional activation of latent Epstein-Barr virus genomes; has been implicated in host cell immortalization; and avoids proteasomal processing and cell-surface presentation. To gain insight into how EBNA1 fulfills these functions, we have profiled cellular protein interactions with...

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Source

Identifiers

PMID: 12783858
DOI: 10.1074/jbc.M303977200

Genes

USP7
PRMT5
SET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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