The K15 Protein of Kaposi's Sarcoma-Associated Herpesvirus Recruits the Endocytic Regulator Intersectin 2 through a Selective SH3 Domain Interaction

doi:10.1021/bi700357s

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Article

The K15 Protein of Kaposi's Sarcoma-Associated Herpesvirus Recruits the Endocytic Regulator Intersectin 2 through a Selective SH3 Domain Interaction

15 Aug 2007

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus, also known as human herpesvirus 8, is closely associated with several cancers including Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. The rightmost end of the KSHV genome encodes a protein, K15, with multiple membrane-spanning segments and an intracellular carboxy-terminal tail that contains several conserved motifs with the potential...

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PMID: 17696407
DOI: 10.1021/bi700357s

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