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Article

Intracellular Localization Map of Human Herpesvirus 8 Proteins

13 Dec 2007

Abstract excerpt

Human herpesvirus 8 (HHV-8) is the etiological agent of Kaposi's sarcoma. We present a localization map of 85 HHV-8-encoded proteins in mammalian cells. Viral open reading frames were cloned with a Myc tag in expression plasmids, confirmed by full-length sequencing, and expressed in HeLa cells. Protein localizations were analyzed by immunofluorescence microscopy. Fifty-one percent of all proteins were localized...

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PMID: 18077714
DOI: 10.1128/jvi.01716-07

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