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Article

KLHL7 promotes TUT1 ubiquitination associated with nucleolar integrity: Implications for retinitis pigmentosa.

Biochemical and biophysical research communications - 9 Dec 2017

Kim Jaehyun, Tsuruta Fuminori, Okajima Tomomi, Yano Sarasa, Sato Ban, Chiba Tomoki

Abstract excerpt

Kelch-like protein 7 (KLHL7) is a component of Cul3-based Cullin-RING ubiquitin ligase. Recent studies have revealed that mutations in klhl7 gene cause several disorders, such as retinitis pigmentosa (RP). Although KLHL7 is considered to be crucial for regulating the protein homeostasis, little is known about its biological functions. In this study, we report that KLHL7 increases terminal uridylyl transferase 1...

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Source

Identifiers

PMID: 29032201
DOI: 10.1016/j.bbrc.2017.10.049

Genes

KLHL7
TUT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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KLHL7 promotes TUT1 ubiquitination associated with nucleolar integrity: Implications for retinitis pigmentosa.PMID 29032201Read ↗

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