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Article

An analysis of the sequence variability of meningococcal fHbp, NadA and NHBA over a 50-year period in the Netherlands.

PloS one - 1 Jan 2013

Bambini Stefania, Piet Jurgen, Muzzi Alessandro, Keijzers Wendy, Comandi Sara, De Tora Lisa, Pizza Mariagrazia, Rappuoli Rino, van de Beek Diederik, van der Ende Arie, Comanducci Maurizio

Abstract excerpt

Studies of meningococcal evolution and genetic population structure, including the long-term stability of non-random associations between variants of surface proteins, are essential for vaccine development. We analyzed the sequence variability of factor H-binding protein (fHbp), Neisserial Heparin-Binding Antigen (NHBA) and Neisseria adhesin A (NadA), three major antigens in the multicomponent meningococcal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23717687
DOI: 10.1371/journal.pone.0065043
PMCID: PMC3663754

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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