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Article

Diversification in immunogenicity genes caused by selective pressures in invasive meningococci.

Microbial genomics - 1 Sept 2020

Kremer Philip H C, Lees John A, Ferwerda Bart, Bijlsma Merijn W, MacAlasdair Neil, van der Ende Arie, Brouwer Matthijs C, Bentley Stephen D, van de Beek Diederik

Abstract excerpt

We studied population genomics of 486 Neisseria meningitidis isolates causing meningitis in the Netherlands during the period 1979-2003 and 2006-2013 using whole-genome sequencing to evaluate the impact of a hyperendemic period of serogroup B invasive disease. The majority of serogroup B isolates belonged to ST-41/44 (41 %) and ST-32 complex (16 %). Comparing the time periods, before and after the decline of...

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Identifiers

PMID: 32776867
DOI: 10.1099/mgen.0.000422
PMCID: PMC7643973

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Source receipt: pubmed, retrieved 7 Sept 2026.

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