Rare variants in GJA5 are associated with early-onset lone atrial fibrillation.

doi:10.1016/j.cjca.2012.08.002

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Article

Rare variants in GJA5 are associated with early-onset lone atrial fibrillation.

The Canadian journal of cardiology - 1 Jan 2013

Christophersen Ingrid E, Holmegard Haya N, Jabbari Javad, Sajadieh Ahmad, Haunsø Stig, Tveit Arnljot, Svendsen Jesper H, Olesen Morten S

Abstract excerpt

BACKGROUND: Genetic factors are believed to be important in early-onset lone atrial fibrillation (AF). The gene GJA5 encodes the gap-junction protein Cx40, which together with Cx43 is responsible for the electrical coupling of the atrial cardiomyocytes. The regulatory single nucleotide polymorphism rs10465885 in GJA5 was recently associated with early-onset lone AF (< 60 years) and was also found to be strongly...

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PMID: 23040431
DOI: 10.1016/j.cjca.2012.08.002

Genes

GJA5

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Rare variants in GJA5 are associated with early-onset lone atrial fibrillation.PMID 23040431Read ↗

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