Article
Linkage disequilibrium between polymorphisms of ABCB1 and ABCC2 to predict the treatment outcome of Malaysians with complex partial seizures on treatment with carbamazepine mono-therapy at the Kuala Lumpur Hospital.
PloS one - 1 Jan 2013
Subenthiran Soobitha, Abdullah Noor Rain, Joseph Joyce Pauline, Muniandy Prem Kumar, Mok Boon Teck, Kee Chee Cheong, Ismail Zakiah, Mohamed Zahurin
Abstract excerpt
PURPOSE: Carbamazepine (CBZ) is used as the first line of treatment of Complex Partial Seizures (CPS) in the Epilepsy Clinic, Neurology Department of Kuala Lumpur Hospital (KLH). More than 30% of the patients remain drug resistant to CBZ mono-therapy. CBZ is transported by the P-glycoprotein (P-g...
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