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Article

Clinical significance of lymphoid enhancer-binding factor 1 expression in acute myeloid leukemia.

Leukemia & lymphoma - 1 Feb 2014

Fu Yuan, Zhu Huayuan, Wu Wei, Xu Jiadai, Chen Tingmei, Xu Bei, Qian Sixuan, Li Jianyong, Liu Peng

Abstract excerpt

Lymphoid enhancer-binding factor 1 (LEF1) is a downstream effector of the Wnt/β-catenin signaling pathway and its dysregulation is associated with a number of malignant diseases such as leukemia. We explored the expression profile of LEF1 in acute myeloid leukemia (AML) and determined its specific prognostic significance in this disease. The LEF1 mRNA level in patients with previously untreated AML was...

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Share to Core Binding Factor Alpha 2 Subunit
Share to fms-Like Tyrosine Kinase 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Lymphoid Enhancer-Binding Factor 1

Share to Nucleophosmin

Share to Oncogene Proteins, Fusion

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Share to RUNX1 Translocation Partner 1 Protein

Source

Identifiers

PMID: 23713453
DOI: 10.3109/10428194.2013.805759

Genes

FLT3
NPM1
PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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