Article
Overexpression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in childhood acute lymphoblastic leukemia.
International journal of laboratory hematology - 1 Oct 2015
Jia M, Zhao H-Z, Shen H-P, Cheng Y-P, Luo Z-B, Li S-S, Zhang J-Y, Tang Y-M
Abstract excerpt
INTRODUCTION: Lymphoid enhancer-binding factor-1 (LEF1) is a target gene and central mediator of the Wnt signaling pathway. High LEF1 expression has been reported as a prognostic marker in several types of hematologic malignancies of adult patients. METHODS: In this study, LEF1 expression was analyzed by real-time polymerase chain reaction (PCR) in 122 children with newly diagnosed ALL treated on the China...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.