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Article

Variations in the human soluble epoxide hydrolase gene and recurrence of atrial fibrillation after catheter ablation.

International journal of cardiology - 9 Oct 2013

Wutzler Alexander, Kestler Christoph, Perrot Andreas, Loehr Lena, Huemer Martin, Parwani Abdul Shokor, Attanasio Philipp, Özcelik Cemil, Schunck Wolf-Hagen, Gollasch Maik, Haverkamp Wilhelm, Boldt Leif-Hendrik

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) of EPHX2 alter sEH activity and are associated with increased [rs41507953 (K55R)] or reduced [rs751141 (R287Q)] cardiovascular risk via modulation of fibrosis, inflammation or cardiac ion channels. This indicates an effect on development and therapy response of AF. This study tested the hypothesis that variations in the EPHX2 gene encoding human soluble epoxide...

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Source

Identifiers

PMID: 23711456
DOI: 10.1016/j.ijcard.2013.05.010

Genes

EPHX2

Variants

rs41507953

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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