Article
Chromosome 4q25 variants and atrial fibrillation recurrence after catheter ablation.
Journal of the American College of Cardiology - 23 Feb 2010
Husser Daniela, Adams Volker, Piorkowski Christopher, Hindricks Gerhard, Bollmann Andreas
Abstract excerpt
OBJECTIVES: This study tested the hypothesis that chromosome 4q25 single-nucleotide polymorphisms (SNPs) associate with atrial fibrillation (AF) recurrence after catheter ablation. BACKGROUND: Recent genome-wide association studies identified 2 SNPs on chromosome 4q25 associated with AF. Although the mechanisms underlying this increased risk are unknown, the closest gene, PITX2, is critical for myocardium...
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