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Article

Common genetic variants and response to atrial fibrillation ablation.

Circulation. Arrhythmia and electrophysiology - 1 Apr 2015

Shoemaker M Benjamin, Bollmann Andreas, Lubitz Steven A, Ueberham Laura, Saini Harsimran, Montgomery Jay, Edwards Todd, Yoneda Zachary, Sinner Moritz F, Arya Arash, Sommer Philipp, Delaney Jessica, Goyal Sandeep K, Saavedra Pablo, Kanagasundram Arvindh, Whalen S Patrick, Roden Dan M, Hindricks Gerhard, Ellis Christopher R, Ellinor Patrick T, Darbar Dawood, Husser Daniela

Abstract excerpt

BACKGROUND: Common single nucleotide polymorphisms (SNPs) at chromosomes 4q25 (rs2200733, rs10033464 near PITX2), 1q21 (rs13376333 in KCNN3), and 16q22 (rs7193343 in ZFHX3) have consistently been associated with the risk of atrial fibrillation (AF). Single-center studies have shown that 4q25 risk alleles predict recurrence of AF after catheter ablation of AF. Here, we performed a meta-analysis to test the...

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Source

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Identifiers

PMID: 25684755
DOI: 10.1161/CIRCEP.114.001909
PMCID: PMC4731871

Genes

KCNN3
PITX2
ZFHX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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