Article
Amplification-refractory mutation system (ARMS) analysis of point mutations.
Current protocols in human genetics - 1 May 2001
Little S
Abstract excerpt
The amplification-refractory mutation system (ARMS) is a simple method for detecting any mutation involving single base changes or small deletions. ARMS is based on the use of sequence-specific PCR primers that allow amplification of test DNA only when the target allele is contained within the sample. Following an ARMS reaction the presence or absence of a PCR product is diagnostic for the presence or absence of...
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