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Article

CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR-186.

Oncotarget - 22 Sept 2015

Zheng Jian, Li Xiao-dong, Wang Ping, Liu Xiao-bai, Xue Yi-xue, Hu Yi, Li Zhen, Li Zhi-qing, Wang Zhen-hua, Liu Yun-hui

Abstract excerpt

The long non-coding RNA Colorectal neoplasia differentially expressed (CRNDE) is a novel gene that activated early in colorectal neoplasia, but it is also up-regulated in many other solid tumors. Herein, the function and underlying mechanism of CRNDE in regulating glioma stem cells (GSCs) were investigated. We found that CRNDE expression was up-regulated while miR-186 expression was down-regulated in GSCs....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26231038
DOI: 10.18632/oncotarget.4509
PMCID: PMC4694835

Genes

XIAP
BAD
MARK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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