High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis.

doi:10.1016/j.jacc.2013.01.100

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Article

High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis.

Journal of the American College of Cardiology - 23 Jul 2013

Silbernagel Günther, Chapman M John, Genser Bernd, Kleber Marcus E, Fauler Günter, Scharnagl Hubert, Grammer Tanja B, Boehm Bernhard O, Mäkelä Kari-Matti, Kähönen Mika, Carmena Rafael, Rietzschel Ernst R, Bruckert Eric, Deanfield John E, Miettinen Tatu A, Raitakari Olli T, Lehtimäki Terho, März Winfried

Abstract excerpt

OBJECTIVES: This study sought to determine whether high intestinal cholesterol absorption represents a cardiovascular risk factor and to link ABCG8 and ABO variants to cardiovascular disease (CVD). BACKGROUND: Plant sterol-enriched functional foods are widely used for cholesterol lowering. Their regular intake yields a 2-fold increase in circulating plant sterol levels that equally represent markers of...

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Identifiers

PMID: 23707316
DOI: 10.1016/j.jacc.2013.01.100

Genes

ABCG8
ABO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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