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Article

High cholesterol absorption: A risk factor of atherosclerotic cardiovascular diseases?

Atherosclerosis - 1 Jul 2023

Simonen Piia, Öörni Katariina, Sinisalo Juha, Strandberg Timo E, Wester Ingmar, Gylling Helena

Abstract excerpt

Lowering elevated low-density lipoprotein cholesterol (LDL-C) concentrations reduces the risk of atherosclerotic cardiovascular diseases (ASCVDs). However, increasing evidence suggests that cholesterol metabolism may also be involved in the risk reduction of ASCVD events. In this review, we discuss if the different profiles of cholesterol metabolism, with a focus on high cholesterol absorption, are atherogenic,...

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PMID: 37290267
DOI: 10.1016/j.atherosclerosis.2023.06.003

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