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Article

Genetic variation and intestinal cholesterol absorption in humans: A systematic review and a gene network analysis.

Progress in lipid research - 1 Apr 2022

Mokhtar Fatma B A, Plat Jogchum, Mensink Ronald P

Abstract excerpt

Intestinal cholesterol absorption varies widely between individuals, which may translate into differences in responsiveness to cholesterol-lowering drugs or diets. Therefore, understanding the importance of genetic variation on cholesterol absorption rates and the complex intestinal cholesterol network is important. Based on a systematic review, genetic variants in seven genes (ABCG5, ABCG8, ABO, APOE, MTTP,...

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PMID: 35390434
DOI: 10.1016/j.plipres.2022.101164

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