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Article

Novel gene-by-environment interactions: APOB and NPC1L1 variants affect the relationship between dietary and total plasma cholesterol.

Journal of lipid research - 1 May 2013

Kim Daniel S, Burt Amber A, Ranchalis Jane E, Jarvik Ella R, Rosenthal Elisabeth A, Hatsukami Thomas S, Furlong Clement E, Jarvik Gail P

Abstract excerpt

Cardiovascular disease (CVD) is the leading cause of death in developed countries. Plasma cholesterol level is a key risk factor in CVD pathogenesis. Genetic and dietary variation both influence plasma cholesterol; however, little is known about dietary interactions with genetic variants influencing the absorption and transport of dietary cholesterol. We sought to determine whether gut expressed variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23482652
DOI: 10.1194/jlr.P035238
PMCID: PMC3622343

Genes

APOB
CETP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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