Article
A composite single-nucleotide polymorphism prediction signature for extranodal natural killer/T-cell lymphoma.
Blood - 12 Aug 2021
Tian Xiao-Peng, Ma Shu-Yun, Young Ken H, Ong Choon Kiat, Liu Yan-Hui, Li Zhi-Hua, Zhai Qiong-Li, Huang Hui-Qiang, Lin Tong-Yu, Li Zhi-Ming, Xia Zhong-Jun, Zhong Li-Ye, Rao Hui-Lan, Li Mei, Cai Jun, Zhang Yu-Chen, Zhang Fen, Su Ning, Li Peng-Fei, Zhu Feng, Xu-Monette Zijun Y, Wong Esther Kam Yin, Ha Jeslin Chian Hung, Khoo Lay Poh, Ai Le, Cheng Run-Fen, Lim Jing Quan, de Mel Sanjay, Ng Siok-Bian, Lim Soon Thye, Cai Qing-Qing
Abstract excerpt
Current prognostic scoring systems based on clinicopathologic variables are inadequate in predicting the survival and treatment response of extranodal natural killer/T-cell lymphoma (ENKTL) patients undergoing nonanthracyline-based treatment. We aimed to construct a classifier based on single-nucleotide polymorphisms (SNPs) for improving predictive accuracy and guiding clinical decision making. Data from 722...
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