Article
CXCR5 polymorphisms in non-Hodgkin lymphoma risk and prognosis.
Cancer immunology, immunotherapy : CII - 1 Sept 2013
Charbonneau Bridget, Wang Alice H, Maurer Matthew J, Asmann Yan W, Zent Clive S, Link Brian K, Ansell Stephen M, Weiner George J, Ozsan Nazan, Feldman Andrew L, Witzig Thomas E, Cunningham Julie M, Dogan Ahmet, Habermann Thomas M, Slager Susan L, Novak Anne J, Cerhan James R
Abstract excerpt
CXCR5 [chemokine (C-X-C motif) receptor 5; also known as Burkitt lymphoma receptor 1 (BCR1)] is expressed on mature B-cells, subsets of CD4+ and CD8+ T-cells, and skin-derived migratory dendritic cells. Together with its ligand, CXCL13, CXCR5 is involved in guiding B-cells into the B-cell zones of secondary lymphoid organs as well as T-cell migration. This study evaluated the role of common germline genetic...
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