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Article

Hodgkin lymphoma risk: role of genetic polymorphisms and gene-gene interactions in DNA repair pathways.

Molecular carcinogenesis - 1 Nov 2011

Monroy Claudia M, Cortes Andrea C, Lopez Mirtha, Rourke Elizabeth, Etzel Carol J, Younes Anas, Strom Sara S, El-Zein Randa

Abstract excerpt

DNA repair variants may play a potentially important role in an individual's susceptibility to developing cancer. Numerous studies have reported the association between genetic single nucleotide polymorphisms (SNPs) in DNA repair genes and different types of hematologic cancers. However, to date, the effects of such SNPs on modulating Hodgkin lymphoma (HL) risk have not yet been investigated. We hypothesized that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21374732
DOI: 10.1002/mc.20747
PMCID: PMC3131460

Genes

XRCC1
NBN
XPC
XRCC3

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