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Article

Galactosylated glycan expression and macrophage sensitivity of Lewis lung tumor cells with different metastatic phenotype.

Journal of cancer research and clinical oncology - 1 Jan 1990

Tímár J, Ladányi A, Lapis K, Moczar E

Abstract excerpt

Biochemical and cytochemical analysis of Lewis lung tumor variants revealed that the low metastatic cells contained more galactose/N-acetylgalactosamine residues in a high-molecular-mass (15-20 kDa) mixed N- and O-glycan fraction than the highly metastatic ones. It was also found that the highly metastatic variant was less sensitive to macrophage cytotoxicity in vitro. The cytotoxicity against the low metastatic...

Topics

Animals
Cytotoxicity, Immunologic
Galactose
Lung Neoplasms
Macrophages
Mice
Mice, Inbred C57BL
Neoplasm Metastasis
Oligosaccharides
Phenotype
Polysaccharides

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Identifiers

PMID: 2370252
DOI: 10.1007/BF01612901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2370252-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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