Article
Expression of glycolipids bearing Lewis phenotypes in tissues and cultured cells of human gynecological cancers.
Japanese journal of cancer research : Gann - 1 Oct 2002
Takehara Kyoko, Kubushiro Kaneyuki, Kiguchi Kazushige, Ishiwata Isamu, Tsukazaki Katsumi, Nozawa Shiro, Iwamori Masao
Abstract excerpt
Transformation-associated expression of Le(b) (Lewis antigen-b) or Le(Y) in human colorectal carcinomas has been well described. To examine the expression of glycosphingolipids (GSLs) bearing Lewis-phenotypes in human gynecological carcinoma-derived cells, we determined the concentrations of all GSLs. Although neither Le(b) nor Le(Y) was present in HEC-108 cells established from the poorly differentiated type of...
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