Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

N-linked sugar chains of mouse B16 melanoma cells and their low-metastasizing variant selected by wheat germ agglutinin.

Glycobiology - 1 Sept 1991

Kawano T, Takasaki S, Tao T W, Kobata A

Abstract excerpt

The N-linked sugar chains of metastasizing mouse B16 melanoma cells (F1) and their wheat germ agglutinin-resistant variant (Wa4-b1) showing a dramatic decrease in metastasizing and tumorigenic potentials were liberated from their membrane glycoproteins by hydrazinolysis, and their structures were comparatively analysed. The results indicated that both cell lines contain high-mannose-type and bi-, tri- and...

Topics

Animals
Carbohydrate Sequence
Epitopes
Genetic Variation
Melanoma
Membrane Glycoproteins
Mice
Molecular Sequence Data
N-Acetylneuraminic Acid
Oligosaccharides
Sialic Acids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Cells, Cultured

Wheat Germ Agglutinins

Source

Identifiers

PMID: 1726466
DOI: 10.1093/glycob/1.4.375

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1726466-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

N-linked sugar chains of mouse B16 melanoma cells and their low-metastasizing variant selected by wheat germ agglutinin.PMID 1726466Read ↗

Altered glycosylation of beta 1 integrins associated with reduced adhesiveness to fibronectin and laminin.Semantic proximity Read ↗

Tumorigenicity and metastatic ability of MmB16 mouse melanoma cell line and its two Aleuria aurantia agglutinin resistant variants.Semantic proximity Read ↗

Expression of fucosyltransferases contributes to melanoma invasive phenotype.Semantic proximity Read ↗

Towards understanding the role of sialylation in melanoma progression.Semantic proximity Read ↗

Characterization of glycosylation and adherent properties of melanoma cell lines.Semantic proximity Read ↗

Comparison of the lectin-binding pattern in different human melanoma cell lines.Semantic proximity Read ↗

Lectin-resistant variants of mouse Lewis lung carcinoma cells. II. Altered glycosylation of membrane glycoproteins.Semantic proximity Read ↗

Lectin-resistant variants of mouse Lewis lung carcinoma cells. I. Selection and in vivo properties.Semantic proximity Read ↗

Sialylation and malignant potential in tumour cell glycosylation mutants.Semantic proximity Read ↗

Characterization of deoxyguanosine-resistant hypoxanthine-guanine phosphoribosyltransferase(-)metastatic variants altered in soybean-agglutinin-binding properties and cell-surface glycoproteins.Semantic proximity Read ↗

Increased expression of highly branched N-glycans at cell surface is correlated with the malignant phenotypes of mouse tumor cells.Semantic proximity Read ↗

Overexpression of lysosomal-type sialidase leads to suppression of metastasis associated with reversion of malignant phenotype in murine B16 melanoma cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.