Article
Phenotypic characteristics of lewis lung carcinoma cells.
Bulletin of experimental biology and medicine - 1 Oct 2002
Gaenko G P, Kozlov A M, Saprykina N S, Dorotnikova E B, Khaidukov S V, Molotkovskii Yu G
Abstract excerpt
We studied adhesive properties and physiological activity in vivo of cells from Lewis lung carcinoma and its metastases. These cells differed in tumorogenic activity and metastatic potential in the syngeneic system. In vivo non-metastasizing cells are characterized by a lower content of surface lectins to tetrasaccharides SiaLex [Neu5Aca2-3Galb1-4(Fuca1-3) GlcNAcb] and SiaLea [Neu5Aca2-3Galb1-3(Fuca1-4)GlcNAcb]...
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