Article
Metastatic phenotype: growth factor dependence and integrin expression.
Anticancer research - 1 Jan 2000
Perrotti D, Cimino L, Falcioni R, Tibursi G, Gentileschi M P, Sacchi A
Abstract excerpt
Homogeneous subpopulations, which are endowed with low or high metastatic potential, were selected from Lewis lung carcinoma (3LL) in an attempt to correlate metastatic phenotype with specific properties of tumor cells. Since the growth of malignant cells at secondary sites could depend on their...
Topics
- Animals
- Antibodies, Monoclonal
- Cell Division
- Cell Line
- Epidermal Growth Factor
- Genotype
- Growth Substances
- Insulin-Like Growth Factor II
- Integrins
- Lung Neoplasms
- Mice
- Models, Genetic
- Neoplasm Metastasis
- Phenotype
- Platelet-Derived Growth Factor
