Article
Lectin-resistant variants of mouse Lewis lung carcinoma cells. I. Selection and in vivo properties.
Clinical & experimental metastasis - 1 Jan 2000
Dus D, Debray H, Strzadala L, Rak J, Kusnierczyk H, Montreuil J, Radzikowski C
Abstract excerpt
The availability of lectin-resistant cell lines with altered carbohydrate moieties in cell surface glycoproteins and glycolipids has greatly facilitated study of the involvement of cellular glycoconjugates in tumor growth and metastasis. We present here a new animal model for metastasis study based on mouse Lewis lung carcinoma LL2 in vitro cell line. From this line, five lectin-resistant variant sublines were...
Topics
- Animals
- Carcinoma
- Cell Line, Transformed
- Genetic Variation
- Lectins
- Lung Neoplasms
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Neoplasm Metastasis
- Neoplasm Transplantation
