CD34 expression and the outcome of nucleophosmin 1-mutated acute myeloid leukemia.

doi:10.1007/s00277-016-2811-y

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Article

CD34 expression and the outcome of nucleophosmin 1-mutated acute myeloid leukemia.

Annals of hematology - 1 Dec 2016

Juncà Jordi, Garcia Olga, Garcia-Caro Montse, Vila Jordi, Zamora Lurdes, Cabezón Marta, Alonso Esther, de la Banda Esmeralda, Rodríguez-Hernández Inés, Ribera Josep Maria, Millá Fuensanta

Abstract excerpt

CD34 positivity has been considered as an adverse prognostic factor in acute myeloid leukemia (AML). Although nucleophosmin 1-mutated (NPM1m) AML is usually CD34 negative, this marker may be expressed at diagnosis or acquired at relapse in a variable number of cases. Our objective was to ascertain if CD34 expression has any influence on the general outcome of this form of acute leukemia. Analysis of clinical...

Topics

Adolescent
Adult
Aged
Antigens, CD34
Biomarkers, Tumor
Female
Follow-Up Studies
Gene Expression Regulation, Neoplastic
Humans
Leukemia, Myeloid, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Mutation

Nuclear Proteins

Nucleophosmin

Treatment Outcome

Young Adult

Source

Open in PubMed

Identifiers

PMID: 27595757
DOI: 10.1007/s00277-016-2811-y

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