Article
CD34 expression and the outcome of nucleophosmin 1-mutated acute myeloid leukemia.
Annals of hematology - 1 Dec 2016
Juncà Jordi, Garcia Olga, Garcia-Caro Montse, Vila Jordi, Zamora Lurdes, Cabezón Marta, Alonso Esther, de la Banda Esmeralda, Rodríguez-Hernández Inés, Ribera Josep Maria, Millá Fuensanta
Abstract excerpt
CD34 positivity has been considered as an adverse prognostic factor in acute myeloid leukemia (AML). Although nucleophosmin 1-mutated (NPM1m) AML is usually CD34 negative, this marker may be expressed at diagnosis or acquired at relapse in a variable number of cases. Our objective was to ascertain if CD34 expression has any influence on the general outcome of this form of acute leukemia. Analysis of clinical...
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