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Article

Variants in CCK and CCKAR genes to susceptibility to biliary tract cancers and stones: a population-based study in Shanghai, China.

Journal of gastroenterology and hepatology - 1 Sept 2013

Xu Hong-Li, Hsing Ann W, Vogtmann Emily, Chu Lisa W, Cheng Jia-Rong, Gao Jing, Tan Yu-Ting, Wang Bing-Sheng, Shen Ming-Chang, Gao Yu-Tang

Abstract excerpt

BACKGROUND AND AIM: Altered motility of the gallbladder is associated with an increased risk of gallstones and can result in biliary tract cancers. Cholecystokinin (CCK) is an important modulator of gallbladder motility which functions by activating CCK type-A receptor (CCKAR). The aim of this study was to determine whether genetic variants in CCK and CCKAR are associated with the risk of biliary tract cancers...

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Identifiers

PMID: 23701593
DOI: 10.1111/jgh.12278
PMCID: PMC3820582

Genes

CCKAR
CCK

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