Article
Polymorphism and Expression Profile of Cholecystokinin Type A Receptor in Relation to Gallstone Disease Susceptibility.
Biochemical genetics - 1 Oct 2016
Kazmi Hasan Raza, Chandra Abhijit, Nigam Jaya, Baghel Kavita, Srivastava Meenu, Maurya Shailendra S, Parmar Devendra
Abstract excerpt
In the present study, we investigated expression pattern of Cholecystokinin type A receptor (CCKAR) in relation to its commonly studied polymorphism (rs1800857, T/C) in gallstone disease (GSD) patients and controls. A total of 502 subjects (272 GSD and 230 controls) were enrolled, and genotyping was performed by evaluating restriction fragments of PstI digested DNA. For analyzing expression pattern of CCKAR in...
Topics
- Adult
- Disease Susceptibility
- Down-Regulation
- Female
- Gallstones
- Genotyping Techniques
- Humans
- India
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Receptor, Cholecystokinin A
- Tissue Distribution
- Young Adult