Article
A computational framework for predicting obesity risk based on optimizing and integrating genetic risk score and gene expression profiles.
PloS one - 1 Jan 2018
Joseph Paule V, Wang Yupeng, Fourie Nicolaas H, Henderson Wendy A
Abstract excerpt
Recent large-scale genome-wide association studies have identified tens of genetic loci robustly associated with Body Mass Index (BMI). Gene expression profiles were also found to be associated with BMI. However, accurate prediction of obesity risk utilizing genetic data remains challenging. In a cohort of 75 individuals, we integrated 27 BMI-associated SNPs and obesity-associated gene expression profiles....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.