Article
Advancement in genetic variants conferring obesity susceptibility from genome-wide association studies.
Frontiers of medicine - 1 Jun 2015
Wang Tao, Jia Weiping, Hu Cheng
Abstract excerpt
Obesity prevalence has increased in recent years. Lifestyle change fuels obesity, but genetic factors cause more than 50% of average variations in obesity. The advent of genome-wide association studies (GWAS) has hastened the progress of polygenic obesity research. As of this writing, more than 73 obesity susceptibility loci have been identified in ethnic groups through GWAS. The identified loci explain only 2%...
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